Melanotan II
A research compound studied for effects on pigment signaling and sexual response.
Whole vial: 10 mg Vial math ↓
Why people look it up
Melanotan II is mostly discussed for tanning and sexual-response effects because small early human experiments measured both.
Skin pigmentationLIMITED HUMAN EVIDENCE
An early human pilot with three participants examined pigmentation. Read source ↗
Sexual responseLIMITED HUMAN EVIDENCE
A small placebo-controlled study in men measured erectile responses. Read source ↗
Long-term safe tanningINSUFFICIENT EVIDENCE
Tiny short-term studies do not answer long-term safety questions. Read source ↗
The labels show the evidence for each claim. Open a row for its source.
Dosage at a glance
Dosage source summary
- Lower example
- 250 mcg
- Middle example
- 500 / 750 mcg
- Higher example
- 1,000 mcg
- How often
- Once daily in the published example
- Time on / time off
- The source separately shows 1–2 weekly maintenance occasions; that is not an agreed cycle.
- Route
- Subcutaneous in that chart
These are initial daily-example rows from one chart, not an approved or established-safe tanning protocol.
These source amounts do not establish a safe human dose for a research vial.
Sources & individual reports
- PeptideDosages published chart; reviewed October 18, 2026
These are initial daily-example rows from one chart, not an approved or established-safe tanning protocol. Source check: 2026-10-18.
Source coverage: 1 reviewed public account. Not a community consensus.
Report 1 ↗First-person account
- Amount reported
- 100 mcg most days; one 200 mcg administration
- How often reported
- daily, according to poster
- Reported duration / cycle
- nearly one month at time of post
- Route (how it was taken)
- not stated
What the account says: Poster also described a sunburn after unprotected sun exposure. A tanning claim does not make UV exposure safe.
Product match & source details
Product match: Product identity and strength were not verified.
r/Melanotan2 firsthand post · Posted: date not independently verified · Reviewed: 2026-10-03.
How much agreement is there? Only one directly checked account is shown. The tiny published pilot is distinct from a community standard.
Public sources last reviewed: 2026-10-03. Product identity and reported results were not independently verified. Source method →
Evidence, sources & vial math
What the research actually showsHuman studies, evidence limits and mechanisms
What has actually been studied?
The human studies were tiny and early. They do not establish long-term effectiveness or safety for online research products.
Evidence limits: Small human studies do not establish an approved use or a regimen for this online vial; long-term safety remains uncertain.
Product status: Research-vial listings are not FDA-approved medicines. Approved-use labels on this page refer only to the named finished prescription product.
Human research
Melanotan II pilot phase 1 pigmentation study 1996
What was found: Two of three volunteers showed increased pigmentation; nausea was reported at most studied levels and one participant had somnolence/fatigue at the highest level.
Main limit: A three-person early safety pilot cannot establish long-term safety, UV protection, or an amount for an online vial.
Study setup and amounts
- Who
- Three healthy male volunteers
- Number of participants
- 3
- Study design
- Single-blind alternating-day saline comparison with dose escalation
- Route
- Subcutaneous study product
- Amount studied
- Started at 0.01 mg/kg and escalated by 0.005 mg/kg steps to 0.025 or 0.03 mg/kg in different participants
- Frequency
- Study injections on weekdays over two weeks, alternating with saline
- Duration
- Two weeks plus one-week follow-up observation
- Outcome measured
- Skin pigmentation and short-term adverse effects
Study and prescription-product amounts describe those sources. They do not select an amount for an online research vial.
How researchers think it might work
Melanotan II imitates a natural pigment-signaling hormone. A tiny human pilot observed darker pigmentation, but its broader effects and safety are not established for this vial.
Show scientific explanation
The 1996 pilot described MT-II as a cyclic alpha-MSH analogue with melanotropic activity in vitro; two of three male participants showed increased pigmentation after subcutaneous exposure. The study was too small to establish a safe clinical regimen. Read supporting source ↗
Vial & syringe mathTurn the vial total and liquid volume into concentration and syringe units
Vial & syringe math
Change the vial total and final liquid volume to see what each U-100 syringe mark represents.
The starting 1 mL is a math example. Enter your final mixed volume to update the numbers.
100 U-100 syringe units = 1 mL. These results assume the labeled amount is evenly mixed through the final liquid volume.
Continue in the calculator →About this listingResearch-use-only status, seller names and additional background
A research material is not intended for human use. Its name or lab report does not establish suitability for a person. What research use only means →
Compiled by PeptideWhy · Scientific sources last checked 2026-10-03 · Editorial policy · Corrections