PT-141
Also called bremelanotide, a compound that activates melanocortin receptors—message receivers involved in several body functions.
Whole vial: 10 mg Vial math ↓
Why people look it up
PT-141 is discussed for sexual desire because bremelanotide is the active ingredient in an approved prescription product for a narrowly defined condition.
Acquired generalized low sexual desire in premenopausal womenFDA-APPROVED USE
Vyleesi is approved for this specific condition and population; this research vial is not Vyleesi. Read source ↗
Applies to the named prescription product, not this research vial.
Male sexual performanceINSUFFICIENT EVIDENCE
The Vyleesi approval does not cover men or establish a benefit for this vial. Read source ↗
General libido boostINSUFFICIENT EVIDENCE
The label is for a defined diagnosed condition, not every cause of low desire. Read source ↗
The labels show the evidence for each claim. Open a row for its source.
Dosage at a glance
Dosage source summary
- How often
- As needed in the labeled population
- Time on / time off
- No more than once in 24 hours; more than eight doses monthly is not recommended on the label.
- Route
- Subcutaneous manufactured prescription product.
Vyleesi uses a fixed-dose autoinjector. Invented low/middle/high bands would misstate its label; this is not a dry-vial protocol.
These source amounts do not establish a safe human dose for a research vial.
Sources & individual reports
Vyleesi uses a fixed-dose autoinjector. Invented low/middle/high bands would misstate its label; this is not a dry-vial protocol. Source check: 2026-10-18.
Source coverage: 1 reviewed public account. Not a community consensus.
Report 1 ↗First-person account
- Amount reported
- 1.3 mg on one occasion
- How often reported
- one reported administration
- Reported duration / cycle
- not stated
- Route (how it was taken)
- injection, as stated by poster; injection type not confirmed
What the account says: Poster described delayed subjective effects. This post does not validate a recurring schedule or product identity.
Product match & source details
Product match: Not the FDA-approved Vyleesi autoinjector and not a verified match to this vial.
r/Peptides firsthand post · Posted: date not independently verified · Reviewed: 2026-10-03.
How much agreement is there? Only one directly checked account is shown. It does not establish a pattern for the dry vial or replace the Vyleesi product label.
Public sources last reviewed: 2026-10-03. Product identity and reported results were not independently verified. Source method →
Evidence, sources & vial math
What the research actually showsHuman studies, evidence limits and mechanisms
What has actually been studied?
The FDA-approved Vyleesi autoinjector is for acquired, generalized low sexual desire in premenopausal women. Its evidence and approval do not automatically apply to a dry PT-141 research vial or to other populations.
Evidence limits: The Vyleesi autoinjector label applies to its finished product and defined population; it does not establish directions for this dry research vial.
Product status: Research-vial listings are not FDA-approved medicines. Approved-use labels on this page refer only to the named finished prescription product.
Human research
RECONNECT bremelanotide phase 3 trials 2019
What was found: Both trials found statistically significant improvements in desire and related distress versus placebo; nausea, flushing, and headache were more frequent.
Main limit: This was a studied finished product in a defined female population. It does not validate the dry PT-141 vial or claims about men or general libido.
Study setup and amounts
- Who
- Premenopausal women with acquired, generalized hypoactive sexual desire disorder
- Number of participants
- 1,267 randomized across two trials; 1,202 in efficacy analysis
- Study design
- Two randomized, double-blind, placebo-controlled phase 3 trials
- Route
- Subcutaneous finished study product
- Amount studied
- 1.75 mg
- Frequency
- As needed in the trial; not a daily schedule
- Duration
- 24 weeks
- Outcome measured
- Sexual-desire and desire-related distress questionnaire scores
Study and prescription-product amounts describe those sources. They do not select an amount for an online research vial.
How researchers think it might work
PT-141, also called bremelanotide, activates melanocortin receptors. The approved Vyleesi product uses this molecule, but exactly how it improves low sexual desire is still unknown.
Show scientific explanation
The Vyleesi label describes nonselective melanocortin-receptor agonism, with MC1R and MC4R binding most relevant at therapeutic exposures, and explicitly says the mechanism of its HSDD benefit is unknown. This label is for a finished autoinjector, not this dry vial. Read supporting source ↗
Vial & syringe mathTurn the vial total and liquid volume into concentration and syringe units
Vial & syringe math
Change the vial total and final liquid volume to see what each U-100 syringe mark represents.
The starting 1 mL is a math example. Enter your final mixed volume to update the numbers.
100 U-100 syringe units = 1 mL. These results assume the labeled amount is evenly mixed through the final liquid volume.
See source amounts as syringe units
Prescription product label. Vyleesi is a finished, single-dose autoinjector for a specific approved use. Its 1.75 mg label amount is not a preparation or dosing instruction for a dry PT-141 research vial. The label says no more than one dose in 24 hours and does not recommend more than eight per month. Read the Vyleesi (bremelanotide) prescribing information ↗
| Source row | Amount | Liquid volume | U-100 units | Full amounts in one vial* |
|---|---|---|---|---|
| Vyleesi label amount | 1.75 mg | — | — | — |
*Whole amounts by mass, before handling loss. Flags identify amounts above the vial total, volumes above the 100-unit scale, or measurements below one unit. Source amounts describe the named product or study; they do not choose an amount for a research vial.
About this listingResearch-use-only status, seller names and additional background
A research material is not intended for human use. Its name or lab report does not establish suitability for a person. What research use only means →
Compiled by PeptideWhy · Scientific sources last checked 2026-10-03 · Editorial policy · Corrections